General Guidelines for Using Trimix

  • Start with prescribed dose. Increase by 5-10 units or less with each trial.
  • The proper dose will produce an erection that lasts 1.5 hours or less.
  • Never re-inject on the same day! Even if the injection does not work.
  • The medication will be effective in 15 to 30 minutes, varies with each patient.
  • Once a week use or less is recommended (to reduce risk of scarring), but no more than three times per week maximum usage.
  • Allow at least 48 hours between each use to avoid priapism (prolonged erection).

Storage of Trimix

  • The medication can be stored in the freezer for 6 months or refrigerator for 3 months
  • It can be thawed and refrozen.
  • The medication will lose potency over time, adjust accordingly but always start with original dose when using a fresh vial to avoid priapism (prolonged erection).

~20 min

Length of time it takes for Trimix to take effect.

48 hrs

Length of time between Trimix dosages to avoid priapism.

Common Side Effects of Trimix

Penile aching

Can be lessened with a formula adjustment

Headache

After injection of Trimix

Bruising or Mild swelling

Of the site of injection

Risks of Trimix

  • #1 Risk is priapism (prolonged erection): priapism is a MEDICAL EMERGENCY.
  • If you have an erection greater than four hours, you must seek medical attention or risk irreparable injury to your penis.
  • Penile scarring from repeated injections, poor technique, or failure to alternate sites

Injecting Trimix

  • Injection location: 10:00-11:00 or 1:00-2:00 o’clock position on the penis, see below.
  • Alternate sides and locations on shaft to reduce risk of scarring and penile curvature.
  • Hold pressure at injection site for two minutes. This will decrease bruising/scarring.
  • For a step-by-step instructional injection video go to: https://vimeo.com/20604125

30 mg version only

Priapism Instructions

Warning: If you have been advised not to take Sudafed (pseudoephedrine HCl) for any reason, the recommendation to try Sudafed to treat priapism does not apply to you.

  • Take 2 tablets of Sudafed, 60mg total of pseudoephedrine (the real kind that you have to ask the cashier / pharmacist at CVS/Walgreens to get behind the counter)
  • Empty your bladder
  • Ejaculate (if you can)
  • Exercise – run around the block, get your heart rate up, to try and divert blood away from the penis and to your muscles
  • Take a shower (hot or cold)
  • Ice pack to the penis

If none of these steps work and you are coming up to 4 hours:

  • If during business hours (8am-5pm), please call 866-367-8768 to schedule a SAMEDAY Appointment.
  • If unable to reach the office or not during business hours, please go to the emergency room.

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